What are proteolytic enzymes?

Gary Moller
4 hours ago
4 min read

Colorful ribbon-like patterns (red and orange) twist and turn on a light gray background, resembling a complex molecular structure.

We have been hearing a lot lately about the health benefits of enzymes, particularly nattokinase. It is even claimed that it might neutralise spike protein. So, what are these enzymes and how do they work?

It just so happens that I have been using enzymes (the proteolytic ones) in the clinic for the best part of 20 years - longer actually. So, I know a lot about them.

Proteolytic enzymes have an extensive range of applications. They are suitable for just about every health issue relating to injuries, toxicities, and just plain old getting old! However, their role is best described as being subtle and longterm - like over months and years. There is nothing overnight with them, and most people won't notice much at all. The health benefits are usually very subtle, like being just that little bit more resistant to infections and ageing better than might be expected. But, for some, the benefits are more than obvious.

Feedback:

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What are proteolytic enzymes?

Proteolytic enzymes (also called proteases) are specialised proteins whose job is to break down other proteins. They do this by cutting the peptide bonds that hold amino acids together in long protein chains.

In nature, these enzymes are everywhere: your stomach uses pepsin, your pancreas makes trypsin and chymotrypsin, and fruits like pineapple and papaya contain bromelain and papain. Inside the body, proteolytic enzymes are critical for digestion, tissue repair, inflammation control, and the constant renewal of cells. As we get older and in times of injury and infections, we need more - not less of these enzymes in our food and via supplementation.

How proteolytic enzymes work

When taken systemically (on an empty stomach so they’re not just used up digesting food), proteolytic enzymes can enter the bloodstream and tissues, where they may:

Break down excess fibrin – fibrin is the fibrous protein involved in blood clotting and scar tissue. Too much fibrin contributes to clots, fibrotic tissue, and poor circulation.
Support healthy circulation – by dissolving fibrin and thinning sticky blood, enzymes may improve blood flow and oxygen delivery.
Reduce inflammation – by breaking down inflammatory protein complexes, they can help calm swelling and pain.
Assist tissue repair – enzymes may clear out damaged proteins, scar tissue, and cellular debris, creating space for fresh healing.
Aid immune regulation – some evidence suggests proteolytic enzymes can reduce inappropriate immune reactions by digesting circulating immune complexes.

This combination makes them especially interesting for cardiovascular disease, lung fibrosis, blood clots, and even conditions where viral or vaccine proteins (such as the COVID spike protein) may linger and trigger ongoing inflammation. I'm being conservative here about my therapeutic claims.

Protocols for use

The general principle with proteolytic enzymes is:

Take them on an empty stomach (30–60 minutes before food, or two hours after)
Build up slowly (start with a low dose and gradually increase to a therapeutic level)
Use daily and consistently for long-term support

For most people, the daily dose is 1–4 capsules, taken at any time of day so long as the stomach is empty.

If a person is also taking medication, especially for circulation disorders, it is always safest to separate the two, even if there is no known interaction. For example, if medication is taken first thing in the morning, the enzymes are best taken later in the day, well away from the timing of the medicine. This helps avoid interactions and ensures both the medicine and enzymes can act as intended.

Warning:

If you are on medication that might interact with these enzymes, although the risks may be very low, please still consult a suitably qualified health professional for advice and guidance before taking them - just to be safe.

Why Serracor-NK is one of the best products available

Not all proteolytic enzyme supplements are created equal. Many are destroyed by stomach acid before they can reach the bloodstream. While it may appear more expensive than some enzyme products, you get what you pay for. Serracor-NK stands out because:

It combines nattokinase (fibrinolytic, clot-dissolving) with serrapeptase (anti-fibrotic, anti-inflammatory), plus supporting enzymes like bromelain and papain.
It includes cofactors like rutin, amla, magnesium, and CoQ10 that enhance antioxidant, mitochondria, and circulatory benefits.
It uses acid-resistant protective technology, helping the enzymes survive stomach acid and remain active by the time they reach the small intestine, where they can be absorbed systemically.
It has a carefully designed protocol: start low (1-2 capsules per day for a week or two), then increase gradually to a therapeutic dose (e.g. 3 capsules, three times daily for a few weeks), then reduce to a maintenance level of 1-2 capsules per day.

This thoughtful formulation and delivery system makes Serracor-NK one of the most reliable proteolytic enzyme products on the market for people wanting cardiovascular, lung, and overall systemic enzyme support.

Conclusion

Proteolytic enzymes are powerful natural agents that help regulate inflammation, clear scar tissue and fibrin, and support healthy blood flow. Taken properly, they may have roles in cardiovascular health, lung function, and possibly in dealing with persistent proteins like those from viruses.

Among available supplements, Serracor-NK offers one of the best-engineered enzyme blends, with careful attention to formulation, dosing protocols, and protection against stomach acid breakdown. For most people, 1–4 capsules daily on an empty tummy is the practical routine, adjusted if necessary in relation to prescription medication timing.